glycerol phenylbutyrate will minimize the level or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Glycerol phenylbutyrate is usually a weak inducer of CYP3A4. Keep track of for lowered efficacy of CYP3A4 substrates that have a slender therapeutic index.

Use Caution/Check. Ethinyl estradiol could inhibit the clearance of benzodiazepines that go through oxidation, thereby growing serum concentrations of concomitantly administered benzodiazepines.

Coadministration of encorafenib with delicate CYP3A4 substrates may well lead to amplified toxicity or lowered efficacy of those brokers.

dasatinib will raise the amount or influence of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

topiramate will lower the extent or result of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Monitor Closely (1)ethinylestradiol will boost the stage or impact of triazolam by System: lowering metabolism.

Givinostat is usually a weak CYP3A4 inhibitor. Closely watch if coadministered with orally administered CYP3A4 delicate substrates for which a small modify in substrate plasma focus may perhaps bring on serious toxicities.

Recommend people that there is a pregnancy publicity registry that monitors pregnancy outcomes in Women of all ages exposed to estazolam all through pregnancy (see PRECAUTIONS, Pregnancy).

dronedarone will improve the degree or outcome of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

talquetamab will increase the level or impact of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Talquetamab results in cytokine release syndrome (CRS) that may suppress exercise of CYP enzymes, leading to elevated publicity of CYP substrates.

Contraindicated (two)itraconazole will boost the stage or impact of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Equally medication will increase QT interval

Check Closely (1)trofinetide will enhance the amount or influence of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Suggest individuals that increased drowsiness and diminished consciousness may possibly boost the Trazodone hazard of falls in a few patients.

Challenges from Concomitant Use with Opioids Suggest both people and caregivers with regard to the challenges of doubtless fatal respiratory despair and sedation when estazolam is applied with opioids and never to work with this sort of medicine concomitantly Except if supervised by a well being treatment supplier.